A2M PRP - The Breakthrough in Treating Osteoarthritis

Living with chronic knee, hip, or shoulder pain? Told your only options are surgery or steroids? There’s new hope. At One Natural Health in Lincoln, we offer A2M-enhanced PRP therapy—an advanced regenerative medicine treatment designed to not just manage pain, but address its root cause.

For moderate arthritis, PRP (Platelet-Rich Plasma) is often effective. But for more advanced cases—especially bone-on-bone—A2M PRP or Bone Marrow Stem Cell Therapy can deliver stronger, longer-lasting relief with fewer treatments.

What Is A2M PRP Therapy and How Does It Help with Arthritis?

Alpha-2-Macroglobulin (A2M) is a large protein naturally found in your blood. It neutralizes enzymes and inflammatory chemicals that break down cartilage.

By combining A2M with PRP, which contains growth factors that promote repair, this therapy both stops the fire (inflammation) and rebuilds the structure (damaged tissue). Patients often require fewer visits than with PRP alone.

PRP vs A2M vs Stem Cell Therapy: Key Differences Explained

PRP (Platelet-Rich Plasma)

Best for: Mild to moderate arthritis, tendon/ligament injuries

Visits: Typically 2-4 sessions

Benefit: Supports healing and reduces inflammation but may fall short for advanced arthritis

A2M-Enhanced PRP

Best for: Moderate to advanced arthritis

Visits: Often 1–2 treatments

Benefit: Blocks cartilage-destroying enzymes and promotes regeneration—stronger and longer-lasting than PRP alone

Stem Cell Therapy (Bone Marrow Derived - BMAC)

Best for: Severe “bone-on-bone” arthritis

Visits: Usually a single procedure

Benefit: Deep cellular regeneration—our most advanced option for long-term structural repair

Conditions Treated with A2M-Enhanced PRP Therapy

A2M PRP isn't just for knees. Its regenerative, anti-inflammatory power can treat a wide range of joint and soft tissue conditions:

• Rotator cuff tears
• Arthritis
• Bone-on-bone joints
• Degenerative Disc Disease
• Tennis Elbow
• Plantar Fasciitis & Foot Pain

A2M PRP is ideal if you:

Have moderate to severe osteoarthritis

Haven’t responded to PRP alone

Want to avoid surgery or steroid cycles

Prefer natural, long-term healing

For severe bone-on-bone knees, stem cell therapy offers the best results, however A2M PRP remains a strong  option for many.

A2M PRP FAQs

Is this different from regular PRP?

Yes. PRP helps repair, but A2M blocks the destructive enzymes causing cartilage loss.

How many treatments will I need?

Most need just 1–2 A2M PRP injections, compared to 2-4 with PRP alone.

Is A2M PRP safe?

Completely. A2M and PRP are made from your own blood, reducing any risk of rejection or complications.

What can I do to support healing?

We recommend:

• Anti-inflammatory nutrition (omega-3s, turmeric, collagen)
• Joint supplements (glucosamine, hyaluronic acid)
• Movement and therapy to maintain flexibility
• Weight reduction for joint relief
• Hyperbaric Oxygen Therapy (HBOT) to speed post-injection healing

Take the First Step Toward Joint Healing with PRP or Stem Cells

You don’t have to live in pain or wait for your joints to get worse. Whether you found us searching for A2M injections Lincoln, non-surgical arthritis treatment, or Alpha 2 Macroglobulin therapy near me—you’re in the right place.